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Behçet's disease
Behçet disease , Behçet's disease, Behçet's syndrome, or Silk Road disease, is one of the rare diseases or syndromes that is the occurrence of a state of inflammation in a number of parts of the body, and these symptoms that appear in a number of parts of the body are Except for the inflammation that occurs in the blood vessels, and it is worth noting that the blood vessels most affected by this disease are the small vessels that are found in the mouth, skin, eyes, and genitals, [1] [2] and it should be noted that the symptoms that appear on the person may be unrelated to each other. In the beginning, [3] It is worth clarifying that Behçet’s disease symptoms appear in the form of seizures, meaning that the patient goes through periods of remission of symptoms and others of their severity and appearance, and the interval between one episode and the next may be several years, [4]Most of the severe symptoms appear years after the onset of the initial symptoms of the disease, and it is very good news that despite the severity of the symptoms caused by Behcet's disease However, adherence to the treatments prescribed by the doctor (which may target the symptoms to alleviate them, or complications to limit their development, or to control the disease in general), the patient can live a good life, in addition to the importance of taking adequate rest and practicing appropriate sports, so effective and appropriate treatment can Reducing the number of times the emergence of disease attacks, meaning increasing the periods of calmness and remission of the disease, so we call on the importance of adhering to the treatment prescribed by the doctor and the need to adhere to his instructions. [5]
To learn more about Behçet’s disease, you can read the following article: ( What is Behç’s disease ) .
Symptoms of Behcet's disease
In fact, the symptoms that appear in cases of Behcet's disease differ from one person to another, in some cases the symptoms may be very simple, and in other cases the symptoms may be very severe. Its statement in some detail is as follows: [4] [3]
Oral and genital sores
They are usually oral soresAs for the sores that appear on the genitals that are caused by Behçet's disease; They are less common or appearing than oral sores, but they are deeper and larger than oral sores, and despite this they usually heal and form scars, and for the site of genital sores in detail, for females, sores may appear in the vulva area in general, especially the vagina, and may affect the neck The uterus as well. As for the appearance of genital sores in men, they are usually on the scrotum, and in a few cases, they may appear on the upper part of the penis.[6]
Skin symptoms
Skin symptoms are also common symptoms of Behçet's disease, which is usually the appearance of acne, as well as a condition scientifically known as Erythema nodosum, and erythema nodosum is a coin-shaped nodule that causes pain when touched, or it may Painful superficial or deep sores appear, and a specialist can tell you that you have Behçet’s disease by observing the skin symptoms, including by conducting a test called the Pathergy test. The skin is scratched or a small hole is made in it; If an ulcer or scar appears, this means that the PATHERGY test result is positive. [7]
ophthalmia
Behcet's disease may cause inflammation in the eyes, and the symptoms of that are: the feeling of pain in the eye, accompanied by sensitivity of the eyes to light, their watering, as well as their redness and a feeling of blurred vision , and it is unfortunate that Behcet's disease may cause a state of vision loss in some cases, in Cases are very severe, and vision loss is more common among Middle Eastern countries and Japan compared to the United States of America. [7]
arthritis
The disease may affect the joints and cause symptoms similar to those of arthritis, such as swelling of the joints, a feeling of pain and stiffness in them, in addition to a sense of warmth, and the joints most affected by Behcet's disease are the joints of the wrists, knees and ankles, in addition to the small joints in The hands, and it is good to mention that the symptoms that are associated with the joints as a result of having Behcet's disease can be successfully controlled in addition to being temporary symptoms, and not permanent as is the case with other diseases. [8]
Behcet's disease can cause inflammation in the intestine and stomach, which causes symptoms related to the digestive system such as indigestion, loss of appetite, and a feeling of pain in the abdomen, in addition to nausea and bloody diarrhea. Damage to the inner lining of the intestine. [8]
Behcet's disease can affect the blood vessels of the lungs, including a condition known as aneurysm, aneurysm, or aneurysms, as a result of the blood vessels being inflamed, and this may eventually lead to severe pulmonary hemorrhage. . [9]
Behcet's disease may affect the central nervous system, as this disease may affect the white matter or part of the brain and the brainstem , which causes the emergence of many symptoms such as headache, confusion, and personality changes. , And the matter may reach the point of a stroke , and in rare cases it causes dementia, and it is worth noting that Behcet's disease may affect the enveloping layers of the brain, which are known as meningitis, which causes inflammation in them, known as Aseptic meningitis. Behind this name, it is attributed that meningitis in this case is not related to any microbe, as it is most often the case. [9]
Vasculitis and the occurrence of blood clots
Behcet's disease causes inflammation in the blood vessels, including arteries and veins , which causes redness and pain in the limbs, and may swell. [10] The fact that the vasculitis associated with Behcet's disease causes blood clots, the most common of which is known as venous thrombosis Deep or varicose veinsDeep vein thrombosis , short for DVT, and deep vein thrombosis is defined as a blood clot in a deep vein in the body, often in the legs, and among the symptoms that may accompany this condition: a feeling of pain and swelling in one of the legs, in addition to warmth The area affected by varicose veins, its redness and a feeling of heaviness in it, often in the back of the leg below the knee, and in fact, varicose veins do not in themselves constitute a critical life-threatening condition, but the blood clot in the leg may travel through the blood vessels and reach the vessels of the lungs Induced a condition known as pulmonary embolism, and pulmonary embolism is a really serious health problem, and its symptoms include: chest pain that worsens when taking a breath and the appearance of blood in coughing, and this problem may appear suddenly or gradually. [11]
In the context of blood clots caused by Behçet’s disease, the possibility of what is known as cerebral venous thrombosis is indicated, but it is rare, and it is defined as the formation of a blood clot in the blood vessel that passes through the dural venous sinuses ) Or dural pockets, and these pockets are located between the outer and inner layers of the brain, and this blood clot may cause an increase in pressure in the brain and disturb the blood flow to it, and the symptoms of this condition: severe headache, which is known as a thunder headache, in which the patient feels a throbbing pain in his head, This pain appears suddenly, and other symptoms include: nerve convulsions, hearing loss in one ear, slurred speech, double vision, in addition to the emergence of symptoms similar to symptoms of stroke, such as muscle weakness or paralysis, but both sides of the body are affected, not as in a stroke Ischemic, where only one limb is affected.[11]
Aneurysm
Vasculitis caused by Behcet's disease may cause swelling or dilation of blood vessels within a condition known as aneurysm as mentioned above, and to understand this condition more clearly it is worth noting that the inflammation in the blood vessel may cause a weakening of its wall, and therefore when the blood passes through The blood vessel increases the pressure on the wall of the weakened blood vessels, which causes the wall to bulge outward, and the fact that an aneurysm usually does not cause any symptoms or signs, but if the weakness in the affected blood vessel is very severe, the blood vessel may burst causing Internal bleeding, in addition to the possibility of suffering from organ failure, and for the symptoms that appear in the event of a burst blood vessel; The fact that varies according to the part in which the blood vessel burst, and in general the possible symptoms can be summarized as: headache , mental confusion, and shortness of breath, Loss of consciousness. [10]
Other symptoms
It is also common for people with Behçet's disease to suffer from other general symptoms, and these symptoms include feeling unusually severe fatigue and fatigue, and this fatigue may be physical or intellectual, and it is unfortunate that this may affect a person's ability to practice various activities. [8]
Symptoms that warrant a review of the doctor
For people who have not been diagnosed with Behçet's disease, it is worth seeing a doctor if any abnormal symptom or sign appears. As for people with Euphoria, they should see a doctor from time to time, especially if new symptoms appear. [12]
References
- ↑ "Behçet disease" , ghr.nlm.nih.gov , Retrieved April 18, 2020. Edited.
- ↑ "Behçet disease" , dermnetnz.org , Retrieved April 18, 2020. Edited.
- ^ A b "Behcet's DISEASE" , Www.mayoclinic.org , Retrieved April 18, 2020. Edited by .
- ^ A b "Behcet's Syndrome type " , Www.vasculitisfoundation.org , Retrieved April 18, 2020. Edited by .
- ↑ "Behçet disease" , rarediseases.info.nih.gov , Retrieved April 18, 2020. Edited.
- ↑ “Symptoms of Behcet's Disease” , www.behcets.com , Retrieved April 18, 2020. Edited.
- ^ A b "Behcet's Disease" , My.clevelandclinic.org , Retrieved April 18, 2020. Edited by .
- ^ A b t "Behçet's DISEASE" , Www.nhs.uk , Retrieved April 18, 2020. Edited by .
- ^ A b "Behcet's Disease" , Www.hopkinsvasculitis.org , Retrieved April 18, 2020. Edited by .
- ^ A b "Behçet's DISEASE" , Www.hse.ie , Retrieved April 18, 2020. Edited by .
- ^ A b "Behçet's DISEASE" , Www.your.md , Retrieved April 18, 2020. Edited by .
- ↑ "Behcet's disease" , www.drugs.com , Retrieved April 18, 2020. Edited.
